Completion bonuses

Successfully complete the game to unlock Professional mode, the “Extras” menu (with “Bonus”, “Separate Ways”, “Assignment Ada”, “Mercenaries”, and “Movie Browser” options), “Wii Edition credits” option (in the “Bonus” menu), Infinite Rocket Launcher, Matilda, and alternate of costumes for Ashley, Leon, and Ada.

Successfully complete the game on the Professional difficulty setting to unlock the PRL 412 weapon.

Successfully complete Separate Ways mode to unlock Ashley’s armored knight and Leon’s suit.

Successfully complete Assignment Ada and Separate Ways mode to unlock the Chicago Typewriter weapon for purchase for one million Pesetas.

Successfully complete Mercenaries mode with all characters with a five star rank to unlock the Handcannon weapon.

Bonus characters in Mercenaries mode

Get a four star or higher rank in the indicated Mercenaries mode level to unlock the corresponding character in Mercenaries mode:

When starting Mercenaries mode, play as Leon and go to the castle. It is much easier to get a good ranking because you can give the enemies a suplex, which almost always kills them in one hit. When you get Jack Krauser from the castle, you can then go to other areas, and it will make it much easier because of his arm.

Hidden videos

There are two hidden cinematics accessible at the title screen. One can be accessed by remaining idle at the main menu until it starts. The other can be seen by pressing B on the Wii-mote at the main menu.

Opening doors quicker

When the “Open” command appears by a door, tap A(2) to kick it open quickly. Doing this will also damage any enemies behind the door at the time you kick.

Easy money

When you get to the church, shoot the bell. Every three times you shoot it, some villagers will appear. Kill them, and you will get anything from Pesetas to ammo and herbs. You can do this as many times as desired. This is effective if you have a lot of ammunition or the Chicago Typewriter.

To earn easy money while playing through the game again, carry an empty Handcannon. It costs no money to have, but you will pick up ammunition for it occasionally. This is worth more than any other type of ammo in the game. After collecting the ammunition, sell it to the merchant. Try using the Chicago Typewriter as your main gun while doing this.

Reticule feedback

Equip your handgun and aim the on-screen reticule at any torch or suspended light. Some times the reticule will turn red and deliver a slight jolt in the Wii-mote to indicate ammunition or a treasure that you can shoot from the light and retrieve. This is a slight advantage not available in previous versions of the game.

Avoiding enemies at start

After you use the chief’s false eye to open the door, walk up the hill until the truck comes at you. Shoot it and get back. Once it explodes, walk back up the hill, but go backwards. Keep going all the way to the castle and you will avoid facing the enemies that would normally appear.

Saving ammunition

If you find yourself surrounded by some parasites of Los Ganados or los Illuminados and do not want to waste ammunition, quickly throw a flash grenade. Once it explodes, it should make the parasites explode, saving your other ammunition.

Alternate controls

Disconnect the Nunchuck when the game loads. When prompted to attach the Nunchuck, attach the Classic Controller instead. You can play classic style Laser Sight and all.

Remove the Nunchuck, and insert a GameCube controller into port one. You will now have a laser sight on your weapons and be able to use all of the GameCube’s normal controls. Note: This is very helpful for sniping.

Defeating El Gigantes

When fighting an El Gigante in its second form, take out your Killer 7 and shoot the parasite, or climb on its back and cut it. Either way, this saves health, ammunition, and a lot of frustration. Note: This is really only beneficial if you do not have one of the special weapons.

Defeating Milita

Instead of shooting for their head, shoot them in the knee, then walk up to them. Instead “Kick”, “Suplex” will appear. This will usually kill them instantly. This will not work if their head is armored.

Defeating the Regenerator

If you find your rifle is empty, you can also defeat the Regenerator by shooting a mine into the spot around the parasite. If it is on its back, shoot out its legs with your handgun, then fire a mine into its back. If this does not work, find out where the parasite is on the Regenerator and try again.

Defeating U3 (It)

While you are in the giant crates, you can maneuver around U3. When you get to the gate, it will follow you. Run around and shoot it, bringing it closer to the explosive barrels. When you run out of barrels, fire either your shotgun or magnum.

Leon hat trick

To make Leon do a special trick with his hat, unlock the gangster costume and Chicago Typewriter. At any point in the game while in Leon’s gangster costume, take out the Chicago Typewriter, aim, and shake the Wii-mote to reload. Leon will make a noise and move his hat. If you do this four times, he will throw his hat in the air and catch it on his head.